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No Warranties or Representations
The data and information presented in this web site are presented in good faith and believed to be accurate. Any and all liability for the content or any omissions including any inaccuracies, errors, or misstatements in such data or information is expressly disclaimed. The web site is compiled for the sole purpose of informing community members of resources and information pertaining to Lyme Disease and its coinfections.
The Canadian Lyme Disease Foundation, Directors and members are not liable for any direct or indirect damages or any damages whatsoever resulting from loss of use, data or profits, whether in an action of contract, negligence or other tortious action arising out of or in connection with the use or performance of information available from this website.
Consult a qualified Lyme Disease literate doctor for medical advice if Lyme Disease is suspect.
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Seminar on Lyme Disease.
April 3rd, 2004
Fort Frances, Ont.
La Place RendezVous Hotel
6:00 pm to 10:00 pm Dinner included
4 MAINPRO M1 CME CREDITS
One speaker will be Dr. Ernie Murakami, B.A., M.D., of Hope, BC. He graduated from the University of BC as a Doctor of Medicine with a B.A. in Bacteriology and Immunology. Dr. Murakami became Clinical Assistant Professor at UBC in 1979, a Clinical Associate Professor in 1995 and Professor Emeritus in 1998. As Preceptor in the Rural Family Practice Program at UBC, he has mentored Fourth Year Medical Students in a clinic setting for 25 years and Medical Resident Students, also in a clinic setting, for the past 10 years. He has been honored an award from UBC for Undergrad Teaching and, on the occasion of UBC's 50th Anniversary, a Gold Medal for his contribution of Lyme Disease teachings.
A Family Physician in Hope since 1960, Dr. Murakami is Medical Director of the Fraser Health Authority. At Fraser Canyon Hospital he is Head of Emergency, President of Medical Staff and Chief of Staff. With his special interest in Lyme Disease, Dr. Murakami researches, publishes, and gives lectures, including an annual lecture on wood ticks to the College of Family Physicians. He has also lectured at World Lyme Disease Conferences, Vancouver in 1994, and in Denver, Colorado in 1999.
Dr. Murakami will be giving a presentation from his perspective as the only doctor in Canada that has diagnosed and treated hundreds of Lyme cases from across Canada.
The second speaker will be Tom Grier B.Sc. - - post grad studies Microbiology/Immunology.
Tom speaks with the unique perspective of both victim and scientist. In 1990 he was diagnosed with MS and lost the use of arms and legs. Later after a corrected diagnosis of Lyme disease and subsequent long term antibiotic treatment he recovered.
Tom has written extensively on Lyme disease since then and is founder of MIBDEC, a not for profit society advancing the study of Lyme disease post mortem.
Here is an outline of his lecture:
Case histories of Lyme Patients: Persistent infection post treatment of Lyme disease
1) Dr. Christina Waniak - Frontal Lobe Dementia in a LD patient who died post treatment for Lyme. Pathology confirmed spirochetes still present in Cerebral cortex
2) Dr. Craig Cleveland –8 months Rx (5 months IV) Cardiac biopsy culture Positive
3) Dr. Ed Masters – Patient has spirochetemia despite six months of Amoxicillin
4) Jim Forris Father’s autopsy –Senile Dementia -autopsy reveals spirochetes in brain by Warthin Stain.
II) Why does it persist?
1) Video Tape of Live Spirochetes
A) Slime Layer, Blebs, polymorphic,
B) Motility –Bb moves out of the blood and enters deep tissues – ie: hides in the Brain
C) Cell Division and Antibiotics: Bacteristatic vs. Bactericidal antibiotics
2) Dr. David Dorward B-Cell Video: Borrelia tropism for B-cells
A) Receptors for B-cells? A rapidearly decline in B-cells,
B) Penetration into B-cells and lysosomal inhibition
B) Cloaking with b-cell membrane
3) Microbiology
A) Tissue Receptors- collagen, neurons, N-Acetyl Glucasamine
B) Endothelial Contact and Tissue Plasminogen-systemic transmision
C) Blood Brain Barrier BBB – TNF-a, Il-1 and Il-6
D) Division, Shared Antigens – Autoimmunity vs. infection load
E) Sequestering – collagen, heart, joints, brain, bladder, GI tract?
F) Blocking Antibodies, B-Cell Membrane Cloaking – Dorward Tape
4) Possible L-forms or Cell Wall Deficient forms – Mattman Slides
III) MS connection – Dr. Gabriel Steiner – 1918-1954 Slides of MS spirochetes
IV) Controversey: Why is there a division in medical opinion
1) Serology vs. Tissue Biopsies, EM, and Culturing
2) ELISA Tests: Ease, Cost and Pitfalls
3) Western Blot tests: New Reporting Standards of Dearborn MI Conference
4) Two Tiered Testing ? Why?
5) Editorial Handout -
V) Conclusions
International Autopsy Tissue Study Needed...MIBDEC
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