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Lyme Disease symptoms vary from person to person. (lymes disease lyme's disease lime disease limes disease)
The data and information presented in this web site are presented in good faith and believed to be accurate regarding Lyme disease (commonly misspelled lymes disease lyme's disease lime disease limes disease) and other related diseases. Any and all liability for the content or any omissions including any inaccuracies, errors, or misstatements in such data or information is expressly disclaimed. The web site is compiled for the sole purpose of informing community members of resources and information pertaining to Lyme Borreliosis Disease and its coinfections. Lyme disease symptoms may vary from person to person.
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Consult a qualified Lyme ( Borreliosis ) Disease literate doctor for medical advice if Lyme Disease is suspect to discuss your Lymes Disease Symptoms.
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J Med Microbiol. 2007 Jan;56(Pt 1):47-51.
The use of local isolates in Western blots improves serological
diagnosis of Lyme disease in Scotland.
* Mavin S,
* Milner RM,
* Evans R,
* Chatterton JM,
* Joss AW,
* Ho-Yen DO.
Microbiology Department, Raigmore Hospital, Old Perth Road,
Inverness IV2 3UJ, UK.
Nine Scottish Borrelia burgdorferi isolates were investigated in IgG
Western blot tests.
Sera previously found to be positive and negative
when tested by routine Western blots prepared from reference strain B.
burgdorferi sensu stricto antigen had different outcomes with these
isolates.
Two isolates, E5 (Borrelia afzelii) and G4 (B. burgdorferi
sensu stricto) performed well, reproducing Western blot-positive results
in 90 and 95 % of tests, respectively. When antigens from both isolates
were incorporated into a single IgG Western blot, the results of a panel
of sera were improved when compared to the routine reference strain IgG
Western blot.
All of the sera positive by the routine Western blot
remained positive using the Scottish isolate antigen mix. Twenty-three
of the 25 negative sera remained negative and two produced an equivocal
result. Of the 15 samples that tested IgG Western blot equivocal with
the B. burgdorferi sensu stricto reference strain, 11 (73 %) became weak
or strong positive when tested with the B. afzelii/B. burgdorferi sensu
stricto antigen mix (chi(2)=14.35, Yates' correction, P<0.001).
In seven
of these, a clinical picture of Lyme disease was consistent with the new
results.
The use of Scottish strains of B. afzelii and B. burgdorferi
sensu stricto to provide antigen for the IgG Western blot improves the
diagnosis of Lyme disease for patients in Scotland.
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