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Lyme Disease symptoms vary from person to person. (lymes disease lyme's disease lime disease limes disease)
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Consult a qualified Lyme ( Borreliosis ) Disease literate doctor for medical advice if Lyme Disease is suspect to discuss your Lymes Disease Symptoms.
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Wien Klin Wochenschr. 2002 Jul 31;114(13-14):616-9.
Development of erythema migrans in spite of treatment with antibiotics after
a tick bite.
Maraspin V, Lotric-Furlan S, Strle F.
Department of Infectious Diseases, University Medical Centre Ljubljana,
Ljubljana, Slovenia. vera.maraspin@kclj.si
OBJECTIVES: The recent information on the appearance of erythema migrans
despite prophylaxis with 200 mg of doxycycline was the stimulus for a search
among our patients for those who developed the skin lesion regardless of
receiving antibiotics after a tick bite.
METHODS: Data were reviewed for
adult patients with erythema migrans diagnosed at our institution from 1994
to July 2001, targeting those who received antibiotics after a tick bite.
RESULTS: Seven of 5056 (0.14%) patients, diagnosed with typical erythema
migrans, developed the skin lesion despite receiving antibiotics after a
tick bite. Antibiotics were prescribed by general physicians: in four cases
as prophylaxis of Lyme borreliosis within one day after tick detachment and
in three cases because of development of acute respiratory tract infection
two, five, and eight days after the bite, respectively. The dosages were as
follows: azithromycin in a total dose of 3 g in three patients and 1.5 g in
the fourth patient, amoxicillin-clavulanic acid 625 mg t.i.d. for ten days
in the fifth patient, amoxycillin 500 mg t.i.d. for seven days followed by
azithromycin 250 mg o.d. for eight days in the sixth, and amoxycillin 500 mg
t.i.d. for eight days in the seventh. The patients (five females and two
males, aged 18-61 years) were referred to our Department on average six
(1-19) days after the appearance of skin lesions. They had typical solitary
(five patients) or multiple (two patients) erythema migrans with the
characteristics usually seen in European patients, except for a rather long
incubation period (median value 28 days, range 10-40 days). All laboratory
tests, including the examination of cerebrospinal fluid in three patients
with the disseminated form of the illness, were within normal range.
Borrelial antibodies were demonstrated in only one patient. A skin biopsy
specimen obtained from the site of the erythema migrans was culture positive
for Borrelia in 2/4 patients.
CONCLUSIONS: Our study did not enable us to
assess the frequency of antimicrobial prophylaxis failure or the efficacy of
individual antibiotics for the prevention of Lyme borreliosis.
However, the
seven patients presented demonstrate that antibiotic prophylaxis for Lyme
borreliosis after a tick bite, at least in Europe, is not entirely
effective.
PMID: 12422612 [PubMed - indexed for MEDLINE]
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