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The data and information presented in this web site are presented in good faith and believed to be accurate. Any and all liability for the content or any omissions including any inaccuracies, errors, or misstatements in such data or information is expressly disclaimed. The web site is compiled for the sole purpose of informing community members of resources and information pertaining to Lyme Borreliosis Disease and its coinfections.
The Canadian Lyme Disease Foundation, Directors and members are not liable for any direct or indirect damages or any damages whatsoever resulting from loss of use, data or profits, whether in an action of contract, negligence or other tortious action arising out of or in connection with the use or performance of information available from this website.
Consult a qualified Lyme ( Borreliosis ) Disease literate doctor for medical advice if Lyme Disease is suspect.
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Lyme disease in China and its ocular manifestations
[Article in Chinese] Zhonghua Yan Ke Za Zhi. 1993 Sep;29(5):271-3.
Liu AN.
Department of Ophthalmology, Chinese Navy General Hospital, Beijing.
The authors report 30 chinese patients of ocular Lyme borreliosis, which is a tick-borne spirochaetal disease involving multiple organ systems. The ocular manifestations begin as conjunctivitis, and then as uveitis, choroidoretinitis, keratitis and vitritis. Diagnosis is based on case history and clinical and laboratory findings. Early cases may be cured by oral antibiotics while intravenous drip of large dosage is needed for advanced cases, with a relapsing rate of 16%. Prolonged systemic corticosteroids may predispose the patient to antibiotic failure; however, topical corticosteroids in combination with antibiotics may minimize ocular inflammation and complications.
PMID: 8168390 [PubMed - indexed for MEDLINE]
Study on ribotyping of Lyme borreliosis spirochete in Guizhou province
Zhonghua Liu Xing Bing Xue Za Zhi.
2003 Dec;24(12):1129-31. Related Articles, Links
[Article in Chinese]
Wang DM, Hao Q, Cai XH, Wan KL, Wang ZX, Chen J.
Guizhou Center for Disease Control and Prevention, Guiyang 550004, China.
OBJECTIVE: To define the main genotypes in Guizhou agricultural areas by molecular epidemiologic investigation of 21 Borrelia burgdorferi sensu lato of Lyme disease spirochetes and to provide the scientific bases for formulating a preventive policy. METHODS: Polymerase chain reaction (PCR) technique was used to amplify the 23S(rrl)-5S(rrf) intergenic spacer, and amplified products were analyzed by restriction fragment length polymorphism (RFLP) and nucleotide sequencing. RESULTS: There were two genospecies in the strains: 20 strains belong to Borrelia valaisiana, 1 strain is Borelia sp. CONCLUSION: Borrelia valaisiana was the main genotype in Guizhou agricultural areas. The harmness of B. valaisiana to human being has been confirmed. In order to efficiently prevent the harmness of agent to the people in Guizhou agriculture areas, we should study the risk further.
PMID: 14761632 [PubMed - indexed for MEDLINE]
Recombinant OspC identification and antigenicity detection from Borrelia burgdorferi PD91 in China
Zhonghua Liu Xing Bing Xue Za Zhi.
2003 Oct;24(10):917-9. Related Articles, Links
[Article in Chinese]
Chen J, Wan KL.
Institute of Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
OBJECTIVE: To recombine OspC gene from Borrelia burgdorferi PD91 of China and expressed it in E. coli for early diagnosis of Lyme disease. METHODS: The OspC gene was amplified from the genome of Borrelia burgdorferi PD91 strain by polymerase chain reaction and recombined with plasmid PET-11D. The recombinant plasmid PET-11D-OspC was identified with PCR, restriction endonuclease analysis and sequencing. The antigenicity was verified with Western Blot. RESULTS: OspC gene was cloned correctly into vector PET-11D. The resultant sequence was definitely different from the published sequence. The recombinant OspC seemed to have had strong antigenicity. CONCLUSION: The findings laid basis for the studies on early diagnosis of Lyme disease.
PMID: 14575608 [PubMed - indexed for MEDLINE]
More on Lyme from China - Click Here
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