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Chronic Fatigue Syndrome Causes

The cause of CFS is unknown, but the condition may be related to infection with effects on the immune system. Several viruses have been studied as possible causes of CFS, but no cause-and-effect relationship has been discovered.

Some evidence indicates that the bacterium Chlamydia pneumoniae (which causes pneumonia and other illnesses)and B.burgdorferi may be a cause of CFS in some cases. People with chronic fatigue syndrome related to C pneumoniae and B.burgdorferi are most likely to respond to antibiotics that kill C pneumoniae, and their CFS symptoms may improve with antibiotic medications such as doxycycline. However, this association is still being debated. Various unrelated infections appear to lead to long-term fatigue in some people.

* Another of the associated infections is the Epstein-Barr virus, or EBV. EBV causes mononucleosis, also called “mono” or the “kissing disease.” Although associated in some cases, EBV does not cause CFS, and CFS is not the same thing as long-term EBV infection or long-term mononucleosis.
* Other unrelated infectious diseases that appear to lead to fatigue include pneumonia, diarrhea, and bronchitis.
* Candida albicans infections (or yeast infections) do not cause CFS.

Other conditions that cause symptoms similar to those of CFS must be ruled out. These include the following:

* Lyme disease
* Adrenal insufficiency
* Malignancy
* AIDS
* Liver disease
* Kidney disease
* Psychosomatic illness
* Hepatitis C
* Thyroid disease

See more about treatable chronic fatigue