Home
Symptoms
Live Discussion
Diagnosis
Treatment
World-wide Support Finder
Library
Research
Lymelinks
Contact
Pets & Lyme
DONATIONS
Drug Info
Medical Dictionary
Board of Directors
Cat scratch fever disease, bartonella, bartonellosis, Philanthropy in Canada, the art of giving, lymes disease, lyme's disease, lime disease, limes disease, lime's disease
    
Click on the graphic to vote for this site as a Starting Point Hot Site.
Lyme Disease in Canada, information and support for Lyme in Canada



</b> lymes disease, lyme's disease, lime disease, limes disease, lime's disease, juvenile arthritis in canada, JA
--
No Warranties or Representations
Lyme Disease symptoms vary from person to person. (lymes disease lyme's disease lime disease limes disease)
The data and information presented in this web site are presented in good faith and believed to be accurate regarding Lyme disease (commonly misspelled lymes disease lyme's disease lime disease limes disease) and other related diseases. Any and all liability for the content or any omissions including any inaccuracies, errors, or misstatements in such data or information is expressly disclaimed. The web site is compiled for the sole purpose of informing community members of resources and information pertaining to Lyme Borreliosis Disease and its coinfections. Lyme disease symptoms may vary from person to person. The Canadian Lyme Disease Foundation, Directors and members are not liable for any direct or indirect damages or any damages whatsoever resulting from loss of use, data or profits, whether in an action of contract, negligence or other tortious action arising out of or in connection with the use or performance of information available from this website.
Consult a qualified Lyme ( Borreliosis ) Disease literate doctor for medical advice if Lyme Disease is suspect to discuss your Lymes Disease Symptoms.
en français
For Physicians
Ticks
Coinfections
Lyme ( borreliosis ) Disease in Canada, information and support for Lyme in Canada
Prevention
Our Stories
Click Here to order our free Lyme Disease Flyer,    Here for our free Lyme Disease Poster ..documents may be copied (to distribute) but edit only for alignment.
Lyme disease in Canada, all you'll need to know about Lyme in Canada

Ophthalmology. 1998 Mar;105(3):459-66.
Comment in: Ophthalmology. 1999 Jan;106(1):1-2.

Bartonella henselae neuroretinitis in cat scratch disease. Diagnosis, management, and sequelae.

Reed JB, Scales DK, Wong MT, Lattuada CP Jr, Dolan MJ, Schwab IR.

Department of Ophthalmology, Wilford Hall Medical Center, Lackland AFB, Texas, USA.

OBJECTIVE: This study aimed to report the long-term outcomes of patients treated with an antibiotic drug combination for Bartonella henselae neuroretinitis.

DESIGN: The study design was a retrospective case series. PARTICIPANTS: Seven consecutive patients with neuroretinitis and cat scratch disease participated.

INTERVENTIONS: Patients underwent medical and ophthalmic evaluations. Blood cultures were obtained, and B. henselae antibody titers were measured. Tuberculosis, Lyme, toxoplasmosis, syphilis, and sarcoidosis were excluded. Patients received oral doxycycline 100 mg and rifampin 300 mg twice daily for 4 to 6 weeks and were observed for an average of 16 months (range, 10-24 months). Formal electrophysiologic testing was performed in three patients after resolution of neuroretinitis.

MAIN OUTCOME MEASURES: The changes in ocular inflammation and visual function associated with treatment were recorded. Follow-up examinations and electrophysiologic testing documented sequelae.

RESULTS: Patients presented following cat exposure with fever, malaise, and blurred vision. Decreased visual acuity (ranging from 20/40 to counting fingers) frequently was associated with dyschromatopsia and afferent pupillary defects. Ophthalmoscopic analysis showed signs of neuroretinitis, including nerve fiber layer hemorrhages, cotton-wool spots, multiple discrete lesions in the deep retina, and stellate macular exudates. B. henselae infection was confirmed with positive blood cultures or elevated immunofluorescent antibody titers or both. Therapy appeared to promote resolution of neuroretinitis, restoration of visual acuity, and clearance of bacteremia. After 1 to 2 years, two eyes had residual disc pallor, afferent pupillary defects, retinal pigmentary changes, and mildly decreased visual acuity. Electrophysiologic studies showed that when compared to the fellow eye, affected eyes had subnormal contrast sensitivity, abnormal color vision, and abnormal visually evoked potentials. Conversely, electroretinograms were normal in all subjects.

CONCLUSIONS: B. henselae is a cause of neuroretinitis in cat scratch disease. Compared to historic cases, doxycycline and rifampin appeared to shorten the course of disease and hasten visual recovery. Long-term prognosis is good, but some individuals may acquire a mild postinfectious optic neuropathy. PMID: 9499776 [PubMed - indexed for MEDLIN