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No Warranties or Representations
Lyme Disease symptoms vary from person to person. (lymes disease lyme's disease lime disease limes disease)
The data and information presented in this web site are presented in good faith and believed to be accurate regarding Lyme disease (commonly misspelled lymes disease lyme's disease lime disease limes disease) and other related diseases. Any and all liability for the content or any omissions including any inaccuracies, errors, or misstatements in such data or information is expressly disclaimed. The web site is compiled for the sole purpose of informing community members of resources and information pertaining to Lyme Borreliosis Disease and its coinfections. Lyme disease symptoms may vary from person to person.
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Consult a qualified Lyme ( Borreliosis ) Disease literate doctor for medical advice if Lyme Disease is suspect to discuss your Lymes Disease Symptoms.
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BARTONELLA
| "Dr. Edward Breitschwerdt, an infectious disease veterinarian
and one of the world's leading researchers of bacteria
called Bartonella, has for the first time documented
evidence that the pathogen may have been passed between
family members." Read More
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Numbers of newly discovered species of Bartonella that are human pathogens are increasing rapidly.
Bartonella has been found in Ixodid ticks and as a co-infection in patients with Lyme Disease. It is also a stand alone infection in many. Bartonellosis can also be caused by insect bites, cat scratch (also called cat scratch fever), playing with rodents, and contact with dog saliva so as a result this, it is a much larger under-reported illness that we are only beginning to understand the long term consequences of if left untreated or not diagnosed early. See a poster presentation of a case study, 'Ataxia following an altercation... with a cat'
Symptoms of Bartonella are almost impossible to distinguish from Lyme, but may include a rash, lymphadenopathy, splenomegaly, hepatomegaly, headache, encephalopathy, somnolence, flu-like malaise, weight loss, sore throat, osteolysis, osteomyelitis, bacillary angiomatosis, and a papular or angiomatous rash. In acute cases, there can be hemolysis with anemia, high fever, weakened immune response, jaundice, abnormal liver enzymes, and myalgias. Endocarditis and myocarditis have been reported. More severe infections are associated with immune deficiency and possibly occurrence of opportunistic infections. As in Lyme Disease and Babesiosis, Bartonella may be transmitted to the fetus in the infected pregnant patient.
Diagnostic tests include serology, blood and CSF PCR, and biopsy of skin lesions and lymph nodes.
In the co-infected Lyme patient, eradication may be difficult. Many antibiotic agents have been reported to be effective, including cephalosporins, fluoroquinolones, erythromycins, gentamicin, rifampin and streptomycin. In practice, these patients seem to do best with a combination regimen that utilizes agents that can penetrate cells. Typical combinations include an erythromycin, plus a fluoroquinolone or rifampin.
Treatment progress is most commonly assessed by PCR post treatment and serial titers.
...from Infectious diseases of the nervous system: pathogenesis and worldwide impact
Paris, France. 10–13 September 2008
BMC Proceedings 2008, 2(Suppl 1):P12
The electronic version of this abstract is the complete one and can be found online at: http://www.biomedcentral.com/1753-6561/2/S1/P12
Published: 23 September 2008
© 2008 Defres et al; licensee BioMed Central Ltd.
Poster presentation
Cat scratch disease is caused by infection with Bartonella henselae of which cats serve as the natural reservoir. The disease is typically characterized by self-limiting regional lymphadenopathy.
Although rare, < 2% of cases, a wide range of neurological manifestations have been described including encephalopathy, cerebellar ataxia, radiculitis and transverse myelitis.
We present a 30 year old immunocompetent man who was admitted to the medical admission unit with a 4 day history of fever and headache. Examination findings were negative for any meningism and only revealed a temperature of 38.6 and an enlarged right epitrochlear lymph node. His 5th digit on his right hand was inflamed at the site of a previous cat scratch 8 weeks prior. He underwent excision biopsy of the lymph node and commenced azithromycin thereafter. Within 2 days his fever had completely settled, however, he developed left sensorineural hearing loss, opthalmoplegia and some nocturnal agitation. CT head at this point excluded any space occupying lesions including abcesses. The following day he was found to have an ataxic gait. Neurological findings showed unremarkable limbs with the exception of limb ataxia. Cranial nerve examination revealed limited abduction bilaterally with associated nystagmus in the contra-lateral eye. In addition there was a left facial weakness involving both the upper and lower face and left sided sensorineural hearing loss. Clinically there was a concern of a Bickerstaff's brainstem encephalitis secondary to the cat scratch disease. Other infections were excluded. His neurological conditions continued to deteriorate over the following 48 hours, becoming progressively encephalopathic and ataxic and he was given a course of intravenous immunoglobulin. His neurological problems gradually resolved over the next 7 days. Later serology and PCR from the lymph node confirmed infection with Bartonella species.
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